Staff/Senior Analytical Scientist

Tue, March 30, 2021

Company Overview

Solid State Pharma Inc. (SSPI) is a leader in the delivery of crystallization engineering services including screening and selection of polymorphs, co-crystals, salts, and crystallization process development and optimization. SPPI has experienced great success with the workflows that have been developed by combining fundamentals of crystallization and solid form science with years of experience and high throughput techniques. SSPI is conducting research on pharmaceutical crystallization engineering, polymorph screening, salt screening, co-crystal screening, chiral resolution, polymorph quantification, converting amorphous material to crystalline solid, chemical and crystallization process modeling. SSPI is working with a large number of pharmaceutical companies across the globe to help them fully understand the solid state and crystallization of their drug candidates.

About Halifax, Nova Scotia

Halifax is one of the most beautiful and historic Canadian cities. Located on the coast of the Atlantic Ocean, there are numerous parks, campsites, trails and rivers around the city for outdoor activities. City life is also superb. With a population of more than 400,000, Halifax is home to many cultural attractions, museums, art galleries, pubs and clubs. The city hosts three major universities and many community colleges. The beautiful Annapolis valley, which is home to the highest tides in the world, and also mountainous Cape Breton, are within a few hours drive from Halifax. Halifax has one of the mildest winters in Canada as well as one of the most pleasant summers, which you can enjoy on the beautiful water front boardwalk.

Summary

The “Analytical Scientist (staff or senior)” position is a key contributor to the ongoing research at SSPI, performing complex analytical work, non-GMP and GMP analytical method development independently or contributing as part of a team to a larger project. This role will be central to our operations working with and reporting to either the Technical Director or Technical VP. The “Analytical Scientist (staff or senior)” will have an opportunity to perform their work with our extensive list of leading-edge equipment. The role will comprise approximately 70-80% hands on lab work.

Job Responsibility

Develop analytical methods and validate them for GMP testing

Perform method transfer where methods are developed by clients and not SSPI

Conduct analytical testing on pharmaceutical compounds (final and intermediate) using X-ray Powder Diffraction (XRPD), Differential Scanning Calorimetry (DSC), Thermal Gravimetry Analysis (TGA), Karl Fisher (KF) Titration, Liquid Nuclear Magnetic Resonance (NMR), Dynamic Vapor Sorption (DVS), Optical and Hot Stage Microscope, Scanning Electron Microscope (SEM), UV-Vis spectroscopy, Particle Size Analyzer, Nano-size Analyzer, BET Surface Area Analyzer, High Performance Liquid Chromatography (HPLC), UPLC, LC-MS, LC-CAD, pKa and Log P/D titrator, Gas Chromatography (GC), etc.

Analyze data that are obtained from experiments and draw conclusions

Mentor and/or supervise more junior analysts

Review reports of more junior analysts

Record all the details of experiments and analytical data as per company SOPs and GMP guidelines

Assess SOPs and enforce compliance with regulatory requirements and GMP guidelines

Work closely with Quality Assurance department on equipment qualification and analytical method qualification

Manage the operation and maintenance of analytical instruments

Write high quality weekly and final reports in accordance with SSPI best practices

Present project results, routinely, to the team in person and through teleconference

Follow the safety rules and housekeeping principles to maintain a clean and safe work environment

Other responsibilities as assigned

Education & Experience

PhD or MSc in chemistry, analytical chemistry or related. Analytical development experience and GMP knowledge are must.

Skills

Sound knowledge in analytical method development and validation under cGMP environment

Knowledge of IQ/OQ/PQ

Knowledge of pharmaceutical analytical instruments

Experience in analytical instrument maintenance and trouble-shooting

Demonstrated to be able to work independently and as part of a team

Ability to use Microsoft office software

Excellent communication skills and the ability to present the result

Comfortable with technical writing in a fast pace environment

Knowledge of project management

Physical Demands

While performing the responsibilities of the job, the employee is required to talk, hear, see, stand, walk, sit, smell and use hands and fingers, to handle or feel. The employee is occasionally required to pick up ordinary weights.

Closing Date

Open until filled.

Contact information

Please submit Resume and cover letter to career@solidstatepharma.com. Three references are needed for candidates who are shortlisted.

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