Some API molecules might not easily form crystalline solid due to higher molecular weight, steric hinderance, or simply the conditions at which they are isolated. These APIs go through a chromatography process in which it is very costly and difficult to scale. This workflow is scientifically designed to help the formation of long range arrangement of molecules to promote crystal formation. The scientific workflow will result in seed crystals, which in turn are used for seeding a scalable crystallization process.
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