Chiral Resolution

This service is specifically designed for chiral resolution of pharmaceutical APIs and intermediates through salt screening using chiral counter ions as resolving agents. Diastereomeric salt formation provides the opportunity of forming a salt of a diastereomer as a crystalline solid, while leaving the other diastereomer in the mother liquor.

Solid State Pharma has a comprehensive list of chiral acids and bases that are proven to be highly successful in resolution of pharmaceutical APIs and intermediates. The chiral acid or base is selected based on the structure of the API or intermediate.